Thesis Topic Details
Topic ID: |
2869 | |
Title: |
Bioinformatic analysis of glycosaminoglycan structures. | |
Supervisor: |
John Whitelock | |
Research Area: |
Biomedical Engineering, Bioinformatics, Biochemistry | |
| Associated Staff | ||
|---|---|---|
Assessor: |
Marc Wilkins | |
| Topic Details | ||
Status: |
Active | |
Type: |
R & D | |
Programs: |
BIOM BINF | |
Group Suitable: |
No | |
Industrial: |
Yes | |
Pre-requisites: |
-- | |
Description: |
Growth factors stimulate cell proliferation and differentiation, functions which make them useful in tissue engineering. The attachment of growth factors to tissue is achieved by glycosaminoglycans (GAGs) such as heparan sulfate. The aim of this project is to map heparan sulfate in tissue engineered cells, and characterise these chains using electrophoresis and mass spectrometry. This project requires the student to utilise existing glycan databases to analyse mass spectroscopy results and develop methods to visualise GAG structures. |
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Comments: |
-- | |
| Past Student Reports | ||
| Joseph COPTY in s1, 2011 Bioinformatic analysis of glycosaminoglycan structures. |
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