Thesis Topic Details

Topic ID:
3236
Title:
Systems Biology of the Methylproteome
Supervisor:
Marc Wilkins
Research Area:
Bioinformatics, Networks, System Modelling
Associated Staff
Assessor:
Bruno Gaeta
Topic Details
Status:
Active
Type:
Research
Programs:
BIOM BINF
Group Suitable:
No
Industrial:
No
Pre-requisites:
--
Description:
We have recently shown that protein arginine and lysine methylation is much more widespread than previously thought. We are now asking the question whether this is a key means by which the cell controls protein-protein interactions? This project will build protein interaction networks, methylation networks and signal transduction networks with the GEOMI visualisation platform. Then, a series of analyses will be done to determine if methylation does control interactions and whether this occurs by itself or in assocation with phosphorylation.
Comments:
The project is with the Systems Biology Initative, a large bioinformatics group in the School of Biotechnology and Biomolecular Sciences. See www.systemsbiology.org.au
Past Student Reports
 
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