Thesis Topic Details

Topic ID:
3352
Title:
Mapping of Zn fingers in the brain
Supervisor:
Merridee Wouters
Research Area:
Bioinformatics, Biochemistry and immunology, Health informatics
Associated Staff
Assessor:
Bruno Gaeta
Topic Details
Status:
Active
Type:
Research
Programs:
BINF
Group Suitable:
No
Industrial:
No
Pre-requisites:
Bioinformatics
Description:
This project is part of the lab's research on molecular pathways underpinning oxidative stress. Recently we surveyed Cys-based Zn ligation sites in solved protein structures and compiled a list of domains containing these sites from the Pfam library of Hidden Markov Models.
Zinc is highly abundant in the brain, but its role is not well understood.
The project aims to map RNA transcripts in the brain which encode proteins containing these Zn-binding domains using the Allen Brain Atlas.
Comments:
Bruno Gaeta, co-supervisor

Past Student Reports
  Justin Jin-Yin WONG in s1, 2013
Mapping of Zn fingers in the brain
 

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