Thesis Topic Details

Topic ID:
866
Title:
EGF mutations associated with disease
Supervisor:
Merridee Wouters
Research Area:
Associated Staff
Assessor:
Bruno Gaeta
Topic Details
Status:
Active
Type:
Research
Programs:
BINF
Group Suitable:
No
Industrial:
Pre-requisites:
An interest in proteins and protein structure. Ability to program in perl. Familarity with a Unix-based environment.
Description:
Mutations in EGF domains are associated with a number of disease phenotypes including Marfan syndrome, Alagille syndrome, spondylocostal dysostosis and various blood diseases. The project aims to use data mining combined with structure and sequence analysis to investigate trends in the nature of mutations associated with disease. Offered in conjunction with Dr Duncan Sparrow and Associate Professor Sally Dunwoodie of the Victor Chang Cardiac Research Institute. A benchwork component is available if desired.
Comments:
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