iHMMune-align web-based access

A HMM-based Partitioning Utility for the Human Immunoglobulin Heavy Chain

Welcome

iHMMune-align is an alignment tool designed specifically for modelling the antibody generation process and identifying the constituent germline genes of a human heavy chain mature variable region sequence, in order to generate an alignment of the rearranged immunoglobulin sequence with its germline genes.

Use the links on the left to download iHMMune-align (Java executable) and access the iHMMune-align web interface.

If you use iHMMune-align in your research please cite:

Gaeta BA, Malming HR, Jackson KJ, Bain ME, Wilson P, Collins AM (2007) iHMMune-align: Hidden Markov model-based alignment and identification of germline genes in rearranged immunoglobulin gene sequences. Bioinformatics 23:1580-1587