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Repertoire FilesDetails of the iHMMune-align default repertoires is provided in the 'Further Information' section. Custom repertoires can be used in place of the iHMMune-align default repertoires. A custom repertoire can be provided for the IGHV, IGHD or IGHJ germline sequences. Germline sequences are required to be in FASTA format as described here. The sequence should be nucleotide and the description line must contain IGHV for V gene germline sequences, IGHD for D gene germline sequences and IGHJ for J gene germline sequences.An example of a custom repertoire for the IGHD genes is provided below. A custom file can be created using this as a template or by compiling FASTA germline sequences from an appropriate source and adding the IGHV/D/J to the description line in a style similar to shown below. |
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