bg.adjust                package:affy                R Documentation

_B_a_c_k_g_r_o_u_n_d _a_j_u_s_t_m_e_n_t (_i_n_t_e_r_n_a_l _f_u_n_c_t_i_o_n)

_D_e_s_c_r_i_p_t_i_o_n:

     An internal function to be used by 'bg.correct.rma'.

_U_s_a_g_e:

     bg.adjust(pm, n.pts = 2^14, ...)
     bg.parameters(pm, n.pts = 2^14)

_A_r_g_u_m_e_n_t_s:

      pm: a pm matrix

   n.pts: number of points to use in call to 'density'.

     ...: extra arguments to pass to bg.adjust.

_D_e_t_a_i_l_s:

     Assumes PMs are a convolution of normal and exponentional. So we
     observe X+Y where X is backround and Y is signal. 'bg.adjust'
     returns E[Y|X+Y, Y>0] as our backround corrected PM.
     'bg.parameters' provides adhoc estimates of the parameters of the
     normal and exponential distributions.

_V_a_l_u_e:

     a matrix

_S_e_e _A_l_s_o:

     'bg.correct.rma'