combineAffyBatch package:matchprobes R Documentation _A _f_u_n_c_t_i_o_n _t_o _c_o_m_b_i_n_e _d_a_t_a _f_r_o_m _d_i_f_f_e_r_e_n_t _A_f_f_y_m_e_t_r_i_x _g_e_n_e_c_h_i_p _t_y_p_e_s _i_n_t_o _o_n_e _A_f_f_y_B_a_t_c_h. _D_e_s_c_r_i_p_t_i_o_n: The function takes a list of AffyBatches and their respective probe sequence information and merges the intensities from the matching probes only into one AffyBatch. _U_s_a_g_e: combineAffyBatch(batch, probepkg, newcdf, verbose=TRUE) _A_r_g_u_m_e_n_t_s: batch: A 'list' of AffyBatches. probepkg: A character vector of the same length as 'batch', containing the names of the probe sequences libraries (for example, 'hgu133aprobe') that go with the AffyBatches. newcdf: Character. The name of the name CDF environment that is to be created. verbose: Logical. If TRUE, messages are printed to the console. _D_e_t_a_i_l_s: Note that batch effects may play an important role, e.g. because of slightly but systematically different reagents or sample treatments in the experiments at led to the data in the different AffyBatches. Thus, please interprete the results of this function with caution. Probe to probe-set mapping: after the common probes between all AffyBatches have been identified, their mapping into probe sets (=the new CDF environment) is obtained from the restriction of the mapping of the first element of 'batch' (see variable 'REFCHIP' in the code). If you want to use this function, please have a look at its code and if necessary, check intermediate results. _V_a_l_u_e: A list with two elements: 'dat', an 'AffyBatch', and 'cdf', an environment that contains the probe-set to probe mapping. The phenoData slot of 'dat' will be empty. This is because in most cases this requires some manual interference. You will need to construct a combined phenoData slot by yourself. _A_u_t_h_o_r(_s): R. Gentleman, Wolfgang Huber _E_x_a_m_p_l_e_s: ## see vignette!